Diligence package

Everything a CLIA-lab quality reviewer needs to evaluate Datamade Genomics — before any data moves, before any LOI. Browse online or download the signed bundle.

READMEstart here

The 7-step walkthrough: run the 5-second offline verify, inspect a real QC report, read the validation report, then decide.

Data Transfer Guideingest + delivery

Three methods (Signed URL, BYOB, Globus) for sending FASTQ to Datamade and receiving results back. Per-customer routing by data location; live status of what's shipped today vs. forthcoming.

Validation Reportv0.1.0-substrate

Customer-facing dossier the Lab's QMS reviewer signs against to authorize LOI. Pins lock manifest, mirrors canonical numbers verbatim, includes verbatim verification commands + expected outputs, sign-off block + deviation block.

Quality Metricscanonical numbers

The numbers source of record: GIAB HG002 30× against v4.2.1 and v5.0q truth sets. Aggregate, in-scope (complement of the published exclusion BED), and per-stratum decomposition.

Intended Use

The boundary statement: secondary analysis only, no interpretation, no diagnosis, no clinical sign-off. Compute layer only; the Lab is the CLIA/CAP lab of record. Forbidden claims explicitly enumerated.

Signing-Key Publishing Policy

The trust model. PEM ≠ trust anchor; the fingerprint pinned in the pilot agreement is. Lab-side 6-step verification checklist, rotation triggers, 18-month deprecation overlap, key archive table.

LOI One-pagertemplate

The Letter of Intent template, with structured slots for key ID and key fingerprint that get pinned at signature time — that's how the trust model anchors.

OpenAPI ContractJSON

Pinned OpenAPI 3 schema for the job-submission REST API. CI catches drift on every commit. LIMS-side adapters should target this contract.

Sample QC ReportJSON

A real QC report from a 2026-05-10 HG002 30× run on an NVIDIA GB10. Every per-sample deliverable ships a JSON QC report like this, validated against QC_REPORT_SCHEMA.

Precomputed Signed Manifestverify offline

A signed manifest + signature.json pair. Verify offline with the genomics-verify CLI against the example public key — exit code 0 proves the signing chain works on your hardware before any LOI motion.

Bundle SHA-256: 1f55a06bc12997064162aeb47247c498b4a404aa1b36200bedffa81bfc7bf31c

Datamade Genomics. Compute layer only; the Lab remains the CLIA/CAP lab of record.